The Development of Muscle Fatigue in Muscle soleus of Rats with Obesity

Authors

  • Dmytro Nozdrenko Educational and Scientific Center "Institute of Biology" of Taras Shevchenko National University of Kyiv
  • Nataliya Nurishenko Educational and Scientific Center "Institute of Biology" of Taras Shevchenko National University of Kyiv
  • Tetyana Matvienko Educational and Scientific Center "Institute of Biology" of Taras Shevchenko National University of Kyiv
  • Danylo Zavodovskiy Educational and Scientific Center "Institute of Biology" of Taras Shevchenko National University of Kyiv
  • Оleksandr Motuziuk Lesya Ukrainka Eastern European National University https://orcid.org/0000-0002-1520-0721
  • Volodymer Belobrov Educational and Scientific Center "Institute of Biology" of Taras Shevchenko National University of Kyiv

DOI:

https://doi.org/10.29038/2617-4723-2016-337-12-212-218

Keywords:

skeletal muscle, obesity, power reduction

Abstract

The process of muscle fatigue in skeletal muscle soleus of rats with the development of obesity was investigated. The results showed that during obesity there is a significant inhibition of contractile activity of skeletal muscles. It was established that a violation of contractile ability of skeletal muscles is a result of the noncholinergic effects of this disease.

References

1. Kostyukov A. I. Fatigue-related changes in electromyogram activity of cat gastrocnemius during frequencymodulated efferent stimulation / A. I. Kostyukov et al. // Neurosci. – 2000. – 97(4). – 801. – Р. 9.
2. Harris R. C., Sale C. Beta-alanine supplementation in high-intensity exercise / R. C. Harris, C. Sale // Med Sport Sci. – 2012. – Р. 59. – Р. 1–17.
3. Thomas C. K. Force-frequency relationships of human thenar motor units / C. K. Thomas et al. // J Neurophysiol. – 1991. – 65(6). – 1509–1916.
4. Kalezic I. Fatigue-related depression of the feline monosynaptic gastrocnemius-soleus reflex / I. Kalezic // J Physiol. – 2004. – 556(Pt1). – Р. 283–296.
5. Harwood H. J. The adipocyte as an endocrine organ in the regulation of metabolic homeostasis / H. J. Harwood // Neuropharmacology. – 2012. – V. 63. – P. 57–75.
6. Rytka J. M. The portal theory supported by venous drainage-selective fat transplantation / J. M. Rytka et al. // Diabetes. – 2011. – V. 60. – P. 56–63.
7. Fontana L. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans / L. Fontana // Diabetes. – 2007. – V. 56. – P. 1010–1013.
8. Kewalramani G. Muscle insulin resistance: assault by lipids, cytokines and local macrophages / G. Kewalramani, P. J. Bilan, A. Klip // Curr Opin Clin Nutr Metab Care. – 2010. – V. 13. – P. 382–390.
9. Akhmedov D. The effects of obesity on skeletal muscle regeneration / D. Akhmedov, R. Berdeaux // Front Physiol. – 2013. – 4. – P. 371.
10. Xіu-Huа Shеn Vіtаmіn Е rеgulаtеs аdіpоcytоkіnе еxprеssіоn іn а rаt mоdеl оf dіеtаry-іnducеd оbеsіty / Xіu-Huа Shеn, Qіng-Yа Tаng, Juаn Huаng, Wеі Cаі // Еxpеrіmеntаl Bіоlоgy аnd Mеdіcіnе. – 2010. – № 235. – P. 47–51.
11. Tullberg M. Effects of lowpower laser exposure on masseter muscle pain and microcirculation / M. Tullberg, P. J. Alstergren, M. M. Ernberg // Pain. – 2003. – 105(1–2). – Р. 89–96.
12. Moopanar T. R., Allen D. G. Reactive oxygen species reduce myofibrillar calcium sensitivity in fatiguing mouse skeletal muscle at 37°C / T. R. Moopanar, D. G. Allen // J Physiol. – 2005. – 564(Pt1). – Р. 189–199.
13. Williams W. O. Huxley’s model of muscle contraction with compliance / W. O. Williams // J Elasticity. – 2011. – 105(1). – Р. 365–380.
14. Debold E. P. The effect of low pH on single skeletal muscle myosin mechanics and kinetics / E. P. Debold, S. E. Beck, D. M. Warshaw // Am J Physiol Cell Physiol. – 2008. – 295(1). – Р. 173–179.

Published

2016-12-17

How to Cite

The Development of Muscle Fatigue in Muscle soleus of Rats with Obesity. (2016). Notes in Current Biology, 12(337), 212-218. https://doi.org/10.29038/2617-4723-2016-337-12-212-218