Notes in Current Biology http://journalbio.vnu.edu.ua/index.php/bio <p>Journal "Notes in Current Biology» was founded <span class="VIiyi" lang="en"><span class="JLqJ4b ChMk0b" data-language-for-alternatives="en" data-language-to-translate-into="uk" data-phrase-index="0">&nbsp;in 2021 as the successor of the journal Scientific Bulletin of the Lesia Ukrainka East European National University.</span> <span class="JLqJ4b ChMk0b" data-language-for-alternatives="en" data-language-to-translate-into="uk" data-phrase-index="1">Series: Biological Sciences, which was founded in 1996 as the Scientific Bulletin of Lesya Ukrainka Volyn State University.</span></span></p> <p>"Notes in Current Biology» is a scientific journal that contains the research results and review articles in the field of biology. The Journal is intended for lecturers, research staff, graduate students and students who specialize in relevant or related fields of science. The articles are published in Ukrainian, Russian or English, which meet the requirements and have received positive recommendations from reviewers.</p> <p>Publication frequency - 2 issues per year.</p> <p><strong>Registered by</strong></p> <p>Ministry of Justice of Ukraine.&nbsp;Certificate of state registration of the printed media № 24734-14674 ПР 4.01.2021</p> <p><strong>Certified by</strong></p> <p>Attestation Board of the Ministry of Education and Science of Ukraine</p> <p>Annex 3 to Order No 735. dated&nbsp;<em>29.06.2021</em></p> <p>Founder and publisher</p> <p>Lesya Ukrainka Volyn National University (43025, Lutsk, Volia ave., 13)</p> en-US lutskeeg@gmail.com (Oleksandr Motuziuk) kuznip@gmail.com (Illya Kuznetsov) Thu, 30 Dec 2021 00:00:00 +0000 OJS 3.3.0.10 http://blogs.law.harvard.edu/tech/rss 60 Assessment of the current state of drained and degraded soils of Western Polissya http://journalbio.vnu.edu.ua/index.php/bio/article/view/550 <p>This work is devoted to the analysis and assessment of the quality of agroecological condition of the soil cover of drained and degraded lands of the Western Polissya zone in order to increase and sometimes restore the fertility of these lands. Based on the results of the obtained analyzes on the content of radioactive elements, in particular cesium-137, the ecological situation of the soil cover of the studied soils was determined, the content of heavy metals in the soil cover and agrochemicals was studied. soil analysis was performed. According to research, it has been established that: 1) even in the area of radiation pollution there are no lands with ecological emer-gency, and the indicators do not exceed 15.1 Bq / m2, 2) heavy metals do not exceed the maximum allowable norms, and sometimes in very small quantities. and need replenishment, 3) to increase the productivity of drained lands it is necessary to increase the content of nutrients in the soil, because the nitrogen content in the soil is very low and low, phosphorus content ranges from very low to medium values, and potas-sium content below average. Studies have also been conducted to determine the reaction of the soil environment. The results of the analyzes showed strong hetero-geneity, as the indicators ranged from very acidic to slightly alkaline, but most of the studied soils are characterized by moderately acidic and weakly acidic reactions of the soil environment.</p> Volodymyr Havrylyuk, Andrii Bortnik, Roman Melymuka Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/550 Thu, 03 Feb 2022 00:00:00 +0000 Free Radical Oxidation of Proteins, Lipid Profile Changes and functional status in Rats liver with acquired Insulin Resistance, Iodine Defficiency and Insulin Resistance in Combination with Iodine Defficiencyin http://journalbio.vnu.edu.ua/index.php/bio/article/view/551 <p>Relevance of the topic – according to modern ideas, insulin resistance and iodine deficiency are deep pathophysiological processes that trigger a cascade of pathological reactions and lead to the formation of a complex of disorders and diseases, so a thorough study of the fundamental mechanisms of their occurrence and development is extremely important.<br>The purpose of the study was the content of protein peroxidation products, lipid spectrum parameters and the level of aminotransferas-es in rats with insulin resistance, iodine deficiency, and insulin resistance in combination with iodine deficiency.<br>Material and methods. The study was performed on 45 white nonlinear rats weighing 120–180 g, which were divided into three exper-imental groups: rats with insulin resistance (1st experimental group, n = 15), animals with iodine deficiency (2nd experimental group), ani-mals with insulin resistance in combined with iodine deficiency (3rd experimental group, n = 15). The control group consisted of 15 intact rats. The content of oxidative protein modification products in the blood and liver tissue of rats was determined. Blood lipid spectrum was assessed by serum levels of triacylglycerols, total cholesterol, high-density lipoproteins and low-density lipoproteins, followed by calculation of the atherogenic factor. The activity of aspartate aminotransferase and alanine aminotransferase was determined in the blood.</p> <p>Results. It was found that the content of products of oxidative modification of proteins in the liver and blood tissue of animals of ex-perimental groups increases. The most pronounced differences in the parameters of the lipid spectrum in relation to the control were found in animals with insulin resistance in combination with iodine deficiency. In animals of this group, the level of cholesterol was twice the control, the content of triacylglycerols increased by 60.32 % compared to the control, the content of low-density lipoproteins exceeded the control by 2.2 times, and high-density lipoproteins decreased relative to the control by 75.74 % . Aspartate aminotransferase and alanine aminotransfer-ase activity in animals of this experimental group exceeded the control by 75 % and 78 %, respectively.<br>Conclusions. In the blood and liver tissue of rats with insulin resistance, iodine deficiency, and insulin resistance in combination with iodine deficiency, the content of free radical oxidation products increases. The content of cholesterol, triacylglycerols, low-density lipopro-teins increases in the blood, the content of high-density lipoproteins decreases, the activity of aspartate aminotransferase and alanine ami-notransferase increases. The most pronounced differences in the indicators in relation to the control were found in animals with insulin re-sistance in combination with iodine deficiency.</p> Iryna Hlozhyk Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/551 Thu, 03 Feb 2022 00:00:00 +0000 Features of clinical-biochemical and molecular-immunological status of patients with COVID-19 depending on age and concomitant pathology http://journalbio.vnu.edu.ua/index.php/bio/article/view/553 <p>The advent (COVID-19) has posed difficult challenges for healthcare professionals in the rapid diagnosis and management of patients with this infection. Although the epidemic of COVID-19 infection has spread worldwide, many issues related to the epidemiolo-gy, diagnosis, clinic, treatment and prevention of this infection remain poorly understood and ambiguous.</p> <p>The article presents the structural characteristics (age, sex, diagnostic) of patients with COVID-19, treated on the basis of KP «Volyn Regional Infectious Diseases Hospital» for 2020-2021, describes the features of hematological and biochemical parameters in patients with COVID-19 in different age groups depending on the concomitant pathology.</p> <p>The revealed correlation between hematological, biochemical, immunological and molecular biological studies in patients with COVID-19 of different sexes and different age categories will allow to develop principles of early diagnosis of the disease, predict the clini-cal course and create a personalized approach to treatment of patients with COVID-19. The results of the study will increase the efficiency of diagnosis and develop criteria for predicting the course of the disease, which will provide adequate therapy and further health and life of pa-tients.</p> Vasyl Pykalyuk, Anna Yushchuk Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/553 Thu, 03 Feb 2022 00:00:00 +0000 Functional changes in rheoencephalography of vertebro-basilar leads in adolescent girls diagnosed with hypertension http://journalbio.vnu.edu.ua/index.php/bio/article/view/554 <p>The aim of our study was to determine the features of cerebral circulation on the background of high blood pressure in ado-lescent girl saged 15–16 years. To achieve this goal, westudied the state of cerebral hemodynamics in adolescent girls with high blood pres-sure and made a comparative analysis of the seindicators. The method of variation statistics and the method of rheoencephalography (REG) were used – a method of diagnostic research that allows to analyze the most important criteria for the condition of cerebral vesselsand blood-flow through them, and is based on measuring changes in cerebralvessels of the vertebro-basilar basin. The following in dicators of rheoen-cephalography were evaluated in the study of cerebral circulation: period of pulse blood filling, time of maximum filling, time of delay, am-plitude of fast filling, dichroic index, rheographic index, average filling speed.</p> <p>As a result of the experiment, it was found that the studied in dicators in girls with high blood pressure (hypertension) are character-ized by statistically lower values of pulse blood filling period (T), maximum filling time (s), dichroic index (A1) and significantly higher average filling rate (Vcp) at p&lt;0.05. This change indicates a decrease in cerebral hemodynamic volume, stroke volume of blood and in-creased arterial tone.<br>The appearance of high blood pressure in adolescence is associated with the risk of its persistence in subsequent years and an unfavor-able prognosis for cardiovascular disease. Therefore, early diagnosis of hypertension in adolescence and adolescence is quite relevant in or-der to conduct effective and timely prevention and treatment, which will prevent a serious prognosis in adulthood. Cerebrovascular disorders are an important component of hypertension, as many brain diseases are accompanied by circulatory dysfunction in the brain.<br>The obtained results and their scientifically substantiated analysis play an important role in clinical practice for a more in-depth study of the pathogenesis of arterial hypertension, development of the necessary methods of its prevention and treatment.</p> Tetyana Shevchuk, Lyudmyla Aponchuk, Yuliia Korniichuk, Natalia Mazurets, Natalia Olishkevich Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/554 Thu, 03 Feb 2022 00:00:00 +0000 Аналіз міопатій, пов’язаних з мітохондріальною дисфункцією http://journalbio.vnu.edu.ua/index.php/bio/article/view/556 <p>Баланс синтезу і споживання білка в м’язах значною мірою залежить від нормальної функції мітохондрій. Мітохо-ндріальна дисфункція невіддільна від виникнення міопатії. У цьому дослідженні аналізуються взаємозв’язки між міопатією, яка ін-дукована статинами, стероїдною міопатією та захворюванням скелетних м’язів, спричиненим алкогольною залежністю, а також взаємозв’язок між цими станами та мітохондріальними аномаліями.<br>Центральний архів Web of Science (WOS) був проаналізований на предмет досліджень алкогольної міопатії з 1999 по 2021 рік, бази даних CiteSpace і WOS використовувалися для оцінки кількості написаних статей, розподілу публікацій за регіонами, дослідницьких організацій, аналізу спільно цитованої літератури та ідентифікація ключового слова.<br>Загалом, після аналізу було виділено 1255 публікацій, при цьому кількість опублікованих статей постійно збільшується. Се-редньорічна кількість публікацій – 54,56. Більшість літератури публікують шість країн. Загалом Сполучені Штати опублікували 383 статтей, що займає перше місце серед усіх країн. Вони також займають центральну позицію у цій сфері досліджень, тобто інші країни більше використовують їх наукові досягнення. Виділено 34 основних автори та 238 статей. За допомогою кластерного ана-лізу виділено 9 категорій, які є значущими кластерами. Ключові слова дослідження спільної появи показують, що такі ключові сло-ва, як наночастинки, апоптоз, мітохондріальні порушення та запалення, є дуже поширеними.</p> Wang Nan, Oleksandr Motuziuk, Dmytro Davydenko Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/556 Thu, 03 Feb 2022 00:00:00 +0000 Features of qualitative and quantitative indicators of blood in persons with cardiovascular disease http://journalbio.vnu.edu.ua/index.php/bio/article/view/557 <p>The purpose of the study was to identify the qualitative and quantitative indicators of the blood system in people diagnosed with coronary heart disease and myocardial infarction. The sample consisted of 40 females, aged 36-60 years, who lived in the Volyn region. All subjects were divided into 2 groups: I - subjects diagnosed with coronary heart disease (20 females); II - subjects with a diagnosis of myocardial infarction (20 females). According to the results, clinical blood parameters were analyzed.</p> <p>It was shown that in adult women with cardiac disorders the most sensitive to the disease were blood counts: erythrocytes, platelets, hemoglobin, hematocrit and erythrocyte sedimentation rate, erythrocyte straightening index, and among the parameters of the leukocyte formula - neutrophils. Subjects with myocardial infarction are characterized by worse values in relation to the "normal" compared to patients diagnosed with coronary heart disease.</p> Tetіana Kachynska, Tetiana Lysyuk, Natalia Lavrenuk, Anna Timoshchuk, Valentina Vovk, Ihor Kotsan Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/557 Thu, 03 Feb 2022 00:00:00 +0000 Features of formation of the dominant phytoplankton complex in water bodies of different types http://journalbio.vnu.edu.ua/index.php/bio/article/view/547 <p>Many years of research (2005–2020) established the peculiarities of the formation of the dominant phytoplankton complex of various water bodies of Ukrainian Polesye (rivers, lakes, reservoirs and quarries). In different seasons, 216 species were dominant, which is 24.6 % of the total number of reservoirs and watercourses of the region identified as part of phytoplankton. In terms of floristics, dia-toms (29.7 % of the total number of dominant species), green algae (24.1 %) and euglena algae (19.4 %) are the richest in the dominant com-plexes.</p> <p>This ratio is inherent in the algae groups of plankton of all studied types of aquatic ecosystems.</p> <p>The greatest similarity in the composition of dominant complexes is characteristic of plankton of rivers and reservoirs created on them (k = 0.48), and a significant similarity was found between the lists of dominant species of lakes and reservoirs formed at the site of flooded quarries (k = 0.41).</p> <p>In most of the studied water bodies the saturation of the dominant complexes did not change significantly during the growing seasons, only in Didovo and Ostrovsky lakes in the summer there was an increase in the number of species that form the dominant complex, with sub-sequent depletion in autumn.</p> <p>Eleven species and intraspecific algal taxa new to Ukrainian Polissya have been identified in the dominant phytoplankton complexes. The appearance of new species in the dominant complexes for the region is largely due to changes in the hydrological and hydrochemical re-gimes of reservoirs and watercourses associated with over-regulation, drainage reclamation, climate change and the emergence of new types of reservoirs at the site of flooded mining quarries.</p> Iulia Sheliuk, Liudmila Konstantinenko Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/547 Thu, 03 Feb 2022 00:00:00 +0000 Spread monitoring of Salvinia natans (l.) all in the Turia river within the city Kovel http://journalbio.vnu.edu.ua/index.php/bio/article/view/548 <p>Resume: Salvinia natans (L.) All. - it is an internationally protected species (included in Annex I of the Bern Convention on the Conservation of European Wildlife and Natural Habitats, the European Red List (category NT Near Threatened), the list of the Interna-tional Union for Conservation of Nature (category Least Concern). At the national level, the species was protected until 2021 (the third edi-tion of the Red Book of Ukraine with conservation status - invaluable), was removed by the Red Book of Ukraine of the fourth edition from 2021. Research has shown that the species is widespread in the Turia River, forming continuous carpets with 100% projective coverage. As part of the planned activities, according to remote sensing, the settlement of S. natans is located in an area of 0.09 ha. According to the Sen-tinel-2 image, the following was determined: the average value of NDVI (as of 15.09.2020) of natural habitats of S.natans is 0.65–0.73, which corresponds to the good condition of vegetation. It was found that the beginning of the species vegetation began in mid-July and lasted until early October. Deterioration of the hydrological regime of the Turia River within the planned activities is accompanied by processes of synantropization of plant groups, the dominance of dangerous invasive species. Studies have shown that the vegetation of the planned area is not valuable from a botanical point of view and is characterized by typical for anthropogenically disturbed areas synanthropic groups and fragmentary inclusions of the dangerous invasive species Artemisia artemisiofolia. In the absence of appropriate measures, these processes will intensify. Planned activities in the area of float and clearing the channel do not pose a threat to the existence of the population of S. na-tans. In addition, the growth of the species on the Turia River contributes to the deterioration of its ecological condition, which is manifested in a decrease in oxygen content in the water during its mass distribution, which can cause suffocation of fish, the aesthetic appearance of the reservoir is lost during the extinction of continuous mats of the species, the recreational opportunities of the reservoir are reduced, etc.</p> Larysa Kotsun, Volodymyr Radzii, Borys Kotsun Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/548 Thu, 03 Feb 2022 00:00:00 +0000 Biodiversity of the floodplain and channel of the Dniester River in the villages of Lipitsa and Kolodruby, Stryi district, Lviv region (Ukraine) http://journalbio.vnu.edu.ua/index.php/bio/article/view/549 <p>According to the results of field research during the vegetation period of 2021, 118 species of vascular plants and 76 species of animals were found in the floodplain of the Dniester River in the Stryj district of the Lviv region. Survey of the site in the village of Lipitsa and the village of Kolodruby were carried out during the vegetation period of 2021 (16.05.2021, 15.06.2021, 24.06.2021 and 03.08.2021). The research territory area is about 1 ha along the right and left banks of the Dniester River. The floodplain is covered with tall grasses (Heracleum sphondylium L., Glyceria notata Chevall., Phragmites australis (Cov.) Trin. ex Steud.), weeds (Arctium lappa L., A. to-mentosum Mill., Echinocystis lobata (Michx.) Torr.et Gray, Veronica filiformis Sm.), underwoods of Rubus caesius L., shrubs and trees Salix alba L., S. acutifolia Willd., S. fragilis L., S. viminalis L., S. pentandra L.<br>The location of the study area within the settlements contributed to a significant anthropogenization of vegetation – aboriginal species account for 39,8 % of the total number of all identified plant species, synanthropic – 60, 2 %, in particular, apophytes – 43,2 %, archaeo-phytes and kenophytes – 17,0 %, which indicates a significant transformation of the spontaneous flora.</p> <p>Among animals molluscs of 6 species, insects – 58 species, amphibians – 1 species, birds – 10 species, mammals – 1 species were noted. All animals are typical and numerous in the study region, among them the usual background species account for 47,4 % of the total number registered, a relatively large proportion of forest and garden pests (26,3 %) and bloodsuckers (14,5 %). The study area was signifi-cantly anthropogenic. Synanthropic plants account for 60,2 %, synanthropic animals – 11,8 %. Registered species do not belong to the re-gional, state and international lists of rare species.</p> Iryna Kuzmyshyna, Kateryna Sukhomlin, Maria Zinchenko, Serhiy Volgin, Oleksandr Zinchenko, Svitlana Dyakiv Copyright (c) 0 http://journalbio.vnu.edu.ua/index.php/bio/article/view/549 Thu, 03 Feb 2022 00:00:00 +0000