Speed-force Musculus Soleus Contraction Parameters Changes in Chronic Alcoholization Rats

Authors

  • Svitlana Zay Lesya Ukrainka Eastern European National University
  • Vladislav Belobrov Taras Shevchenko National University of Kyiv
  • Dariya Vulitska Taras Shevchenko National University of Kyiv
  • Oleksandr Nozdrenko Taras Shevchenko National University of Kyiv
  • Olga Abramchuk Lesya Ukrainka Eastern European National University
  • Oleksandr Motuziuk Lesya Ukrainka Eastern European National University

DOI:

https://doi.org/10.29038/2617-4723-2017-362-13-90-97

Keywords:

chronic alcoholization, force of contraction, musculus soleus

Abstract

Chronic alcoholism leads to dysfunctions of skeletal muscles, including atrophy with concomitant loss of muscle mass, changes in the movements, and general impairment of mobility. These disorders are classified as alcoholic myopathy which is accompanied by severe metabolic and physiological changes. The study concerns changes of m. soleus contraction macroparameters under conditions of an alcoholic myopathy development in rats. The inability to adequately process the impulse signals of the stimulation pattern of the muscle with the described pathologies was shown. Taking into account the possible increase in the duration of the latent period, which may be caused by a delay in generation of the action potential and conductivity impairment, the impulses do not coincide with the phase of the latent period, but are shifted towards the phase of muscle contraction. This leads to the impairment in the effectiveness of tetanus contractions frequency summation. This functional feature of the myopathic muscles is important for the central motor command to be adequately and correctly implemented by the muscular apparatus. Hence, alcoholic myopathy can be mainly revealed during precise positioning movements and precise aimed changes in joint angles.

Published

2017-12-13

How to Cite

Speed-force Musculus Soleus Contraction Parameters Changes in Chronic Alcoholization Rats. (2017). Notes in Current Biology, 13(362), 90-97. https://doi.org/10.29038/2617-4723-2017-362-13-90-97